Preheat oven to 400 degrees and lightly grease a large casserole or baking dish. Next, Cook macaroni pasta according to package's instructions. Drain and set aside.
In a large pan or skillet melt the 3 tablespoons butter. Stir in flour. Slowly and gradually whisk in milk until a sauce forms. Stir corn starch into evaporated milk until dissolved, then add to pan and whisk to combine.
Add dijon mustard, Italian seasoning, salt and pepper, cream cheese, and 1 1/2 cups pepperjack cheese and stir until cheeses are melted and combined with the sauce.
Stir noodles into the sauce. Transfer to prepared casserole/baking dish. Sprinkle remaining pepperjack cheese over the top.
Next make the topping. In a pan on the stove, melt butter. Add breadcrumbs and Italian seasoning and stir over medium-high heat until breadcrumbs begin to brown. Sprinkle over pasta.
Bake, uncovered, for about 10-15 minutes. Allow to cool slightly and serve.